About Parabilis Medicines

Parabilis Medicines is a clinical‑stage biopharmaceutical company dedicated to creating extraordinary medicines for patients with serious diseases by unlocking biologically important targets long considered undruggable. The company has pioneered a current class of alpha‑helical peptides – Helicons™ – capable of modulating intracellular proteins that have historically been beyond the reach of conventional medicines. The company’s lead investigational medicine, zolucatetide, is the first and only direct inhibitor of the β‑catenin:TCF interaction, a central node in the Wnt/β‑catenin pathway that has eluded drug developers for decades.

Zolucatetide is being evaluated in the clinic across multiple Wnt/β‑catenin‑driven diseases, including desmoid tumors, familial adenomatous polyposis (FAP) and a range of other solid tumor indications. Beyond zolucatetide, Parabilis is advancing additional Helicon‑based programs focused on other challenging targets where we believe our medicines could have life‑altering impact.



For more information, visit www.parabilismed.com or follow us on LinkedIn.

What's the Opportunity?

Parabilis Medicines is seeking a highly motivated and driven Associate Director, Toxicology to lead nonclinical safety programs across a diverse pipeline built on Parabilis’ clinically validated Helicon™ pipeline. This is a hands‑on scientific leadership role embedded in the discovery and early development organization, with accountability for advancing candidates from lead optimization through IND filing and beyond. The successful candidate will serve as the nonclinical safety lead on cross‑functional project teams, working autonomously to define strategy, drive execution, influence candidate selection, and ensure robust safety assessment across our pipeline.

- Discovery‑Stage / IND‑Enabling Safety Engagement Partner with discovery teams during Pre‑LO/LO to identify safety liabiliti

📌 Associate Director, Toxicology (Town of Cambridge)
🏢 Doist
📍 Town of Cambridge