Principal Clinical Scientist (AI Training)

About The Role
What if your deep expertise in clinical trial design and regulatory science could directly shape how AI understands and reasons about clinical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to cutting-edge AI research workflows. You'll work alongside world-leading AI labs to ensure that clinical data used to train and evaluate advanced AI systems meets the exacting standards expected in real-world regulatory submissions — FDA, EMA, and beyond. This is a fully remote, flexible contract role built for experienced clinical scientists who want to apply their expertise in a high-impact, forward-looking environment.
• Organization: Alignerr
• Type: Hourly Contract
•

Location:
Remote
• Commitment: 10–40 hours/week

What You'll Do
• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
• Provide expert, structured feedback that directly improves how AI models reason about clinical trial data, outcomes, and evidence
• Help establish the quality bar for clinical content used across frontier AI research projects Who You Are




• Senior clinical scientist with hands-on experience designing clinical trial protocols intended for regulatory submission
• Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent bodies
• Strong grounding in clinical research methodology, biostatistics, translational science, or a closely related discipline
• Naturally rigorous and detail-oriented — you hold clinical data to the highest standards
• Comfortable working independently and delivering structured, high-quality feedback in a remote setting Nice to Have
• Prior experience with data annotation, data quality frameworks, or AI evaluation systems
• Background in pharmacology, oncology, rare disease, or other specialized therapeutic areas
• Familiarity with AI tools or content evaluation platforms Why Join Us
• Work directly on frontier AI systems making a real impact on clinical and biomedical research
• Influence how AI understands, evaluates, and communicates real-world clinical evidence at scale
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level project work
• Collaborate with leading AI research teams on some of the most ambitious AI projects in existence
• Potential for ongoing work and contract extension as new projects launch

📌 Principal Clinical Scientist (Sydney)
🏢 Alignerr
📍 Sydney