Flexible appointment available as either one full-time position (1.0 FTE) or two part-time positions operating under a job-share arrangement for a Senior Scientist Provide scientific leadership and operational oversight for a world-leading translational research laboratory Base Salary $131,108 p.a. (pro-rata for part-time appointments) + 17% superannuation

About the opportunity The Centre for Organ Assessment, Repair & Optimisation (COARO) is seeking experienced Senior scientists to provide scientific leadership and day-to-day operational oversight of an established translational research laboratory focused on ex vivo perfusion of human organs. This is an exciting opportunity to join a highly funded and rapidly growing research program that has developed a world-leading platform enabling long-term ex vivo organ preservation for up to seven weeks under near-physiological conditions. This unique platform creates opportunities to investigate organ repair, regeneration, and metabolic adaptation over extended, clinically meaningful timescales. The laboratory is entering a significant growth phase, including the world's first clinical trial of long-term organ preservation prior to transplantation. These positions represent the first dedicated biological leadership appointments within the program and will play a critical role in defining the mechanistic framework underpinning sustained organ repair and regeneration. Key research areas include understanding organ metabolism during extended ex vivo perfusion, organ repair, remodelling and regeneration, with an initial focus on liver research while extending to other organs including kidney and pancreas.

Appointment Structure: This opportunity may be appointed as either: one full-time Senior Scientist position (1.0 FTE), or two part-time Senior Scientist positions working collaboratively under a co-leadership model.

Specialist Area 1: Cellular Metabolism and Mitochondrial Physiology You will bring deep scientific expertise in cellular metabolism, mitochondrial biology, and physiology to investigate the metabolic and physiological changes occurring during extended ex vivo organ preservation.

Specialist Area 2: Cellular Repair and Regeneration You will bring expertise in tissue repair mechanisms, regeneration biology, and cellular recovery pathways to investigate organ regeneration and functional recovery within ex vivo systems.

- provide scientific leadership and domain expertise in metabolism, physiology, repair, or regeneration biology
- lead hands-on experimental design, execution, optimisation, and troubleshooting
- analyse and interpret biological samples using molecular and cellular techniques including western blotting and microscopy
- process,



analyse and integrate complex multiomic datasets including metabolomics, lipidomics and transcriptomics
- contribute to the development of the laboratory's scientific strategy, hypotheses, and research priorities
- provide oversight and coordination across multiple research streams
- supervise PhD students and early-career researchers
- coordinate day-to-day laboratory operations and research activities
- collaborate effectively with engineers, scientists, and technical staff in a multidisciplinary workplace
- contribute to publications, grant reporting, and the ongoing growth of the research program
- maintain oversight of project progress, deliverables, and experimental outcomes
- integrate findings across projects to generate meaningful biological insights

About you PhD with postdoctoral research experience demonstrating scientific independence demonstrated expertise in one or more of the following areas: cellular metabolism, mitochondrial biology, organ injury, tissue repair or regeneration biology strong publication record in high-impact peer-reviewed journals proven ability to design, conduct and interpret complex experimental studies experience working with and integrating multiomic datasets demonstrated contribution to sustained, multi-phase research programs experience within translational, biomedical, or clinically adjacent research environments, ideally involving human tissue or organ systems demonstrated ability to maintain oversight of multiple projects while managing experimental detail outstanding organisational, communication and stakeholder engagement skills demonstrated ability to work effectively in multidisciplinary and collaborative research environments commitment to mentoring and developing early-career researchers. Desirable experience working within collaborative or co-leadership models demonstrated ability to balance scientific leadership and hands‑on research activities established commitment to supervision, mentoring, and research training

To keep our community safe, please be aware of our COVID safety precautions which form our conditions of entry for all staff, students and visitors coming to campus.

Sponsorship / work rights for Australia You must have unrestricted work rights in Australia for the duration of this employment to be eligible to apply. Visa sponsorship is not available for this appointment.





Pre-employment checks and declarations Your employment is conditional upon the successful completion of all pre-employment or background checks required for the role in terms satisfactory to the University. Also, to meet the University’s obligations under the National Higher Education Code to Prevent and Eliminate Gender-Based Violence you will be asked to declare if you have been investigated for, or found to engaged in, sexual harm or gender-based violence in the course of previous employment or in a legal process. Similarly, your ongoing employment is conditional upon the satisfactory maintenance of all relevant clearances and background check requirements. If you do not meet these conditions, the University may take any necessary step, including the termination of your employment.

EEO statement At the University of Sydney, our shared values are trust, accountability and excellence and we strive to be a place where everyone can thrive. We are committed to creating a university community that thrives through diversity and reflects the wider community that we serve. We deliver on this through our commitment to diversity and inclusion, evidenced by our people and culture programs, as well as key strategies to increase participation and support the careers of Aboriginal and Torres Strait Islander People, women, people living with a disability, people from culturally and linguistically diverse backgrounds, and those who identify as LGBTQIA+. We welcome applications from candidates from all backgrounds. We are proud to be recognised as an Australian Workplace Equality Index (AWEI) Platinum Employer. Find out more about our work on diversity and inclusion.

Applications Close Thursday 19 November :59 PM

Our team is expanding, and we want to hire the most talented people we can. Continued success depends on it! So once you've had a chance to explore our current open positions, apply to the ones you feel suit you best and keep track of both your progress in the selection process, and new postings that might interest you! The University values are excellence, trust and accountability. The University of Sydney is committed to diversity and social inclusion. Applications from people of culturally and linguistically diverse backgrounds; equity target groups including women, people with disabilities, people who identify as LGBTIQ; and people of Aboriginal and Torres Strait Islander descent, are encouraged. The University reserves the right not to proceed with any appointment. The University of Sydney may conduct routine pre-employment checks before an appointment is made. Want to know more about working at the University of Sydney?

#J-18808-Ljbffr

📌 Senior Scientist (Australia)
🏢 University Of Sydney
📍 Australia