About Iovance Biotherapeutics, Inc.

Iovance Biotherapeutics , Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com .

Amtagvi® and its accompanying design marks, Proleukin ® , Iovance ® , and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners.

Information on Iovance's broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com .

Overview

Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumour-infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognise and attack diverse cancer cells in each patient. The company's first product, AMTAGVI (lifileucel),



an autologous T-cell therapy using TIL, was recently approved by the Therapeutic Goods Administration (TGA) and is indicated for the treatment of advanced melanoma. Iovance is preparing to launch this novel treatment in the Australian market.

The Commercial Lead, Australia is the senior commercial leader accountable for establishing, commercialising and scaling Iovance's business in the Australian market. This role owns the Australian commercial strategy and profit-and-loss performance, including revenue, operating expenses, forecasting, resource allocation and achievement of business objectives for AMTAGVI and Proleukin. The Commercial Lead will direct the full sales cycle-from market development, account planning, referral generation and patient identification through treatment-centre activation, completed patient infusions, revenue generation and ongoing account growth. This individual will report directly to the SVP, Global Access, Operations and Proleukin.

The Commercial Lead will lead the authorisation and commercial activation of AMTAGVI treatment centres and provide operational and quality oversight after authorisation. The individual will build executive and clinical relationships across treatment centres and referral networks; ensure medical, nursing, laboratory, pharmacy,



quality and administrative stakeholders are prepared to deliver TIL therapy; and align internal functions to move eligible patients from identification and referral through tumour procurement, manufacturing coordination, treatment scheduling, completed infusion and revenue recognition.

As the senior business leader for Australia, the individual will set the country commercialisation strategy, lead launch and market development, and be accountable for commercial performance in the near term and in preparation for national public access. The role will represent the Australian business in global planning, investment, forecasting and performance discussions and will build the commercial capabilities and organisation required as the market grows.

Location: Melbourne or Sydney preferred. This role requires regular travel across Australia, including Queensland, Current South Wales, Victoria, Western Australia, and other states and territories as business needs dictate.

Essential Functions and Responsibilities

- Own and lead the Australian commercialisation strategy, launch plan and ongoing business performance for AMTAGVI and Proleukin.
- Hold profit-and-loss accountability for the Australian business, including revenue, operating expenses, forecasts, budgets, investments, resource allocation and profitability.
- Establish annual and long-range commercial plans, performance measures and resource priorities aligned with global business objectives.
- Lead the full sales cycle across authorised treatment centres and referral networks, from opportunity identification, account planning and customer education through patient identification, referral, treatment scheduling, completed infusion, revenue generation and ongoing account growth.
- Achieve patient infusion, demand and revenue targets for AMTAGVI and Proleukin while maintaining compliance with applicabl

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📌 Commercial Lead, Australia (Sydney)
🏢 iovancebiotherapeutics
📍 Sydney