Join Nucleus Network as a Principal Investigator and help advance medicine while building a rewarding career in clinical research.

As the world's leading Phase 1 clinical trials specialist, with facilities across Australia, the USA, and the UK, we partner with global pharmaceutical and biotechnology companies to help bring new medicines to patients.

Why Join Nucleus Network?

- Work with purpose and contribute to research that improves lives worldwide.
- Ask better questions and find smarter ways of working in an environment that values innovation and continuous improvement.
- Start here, go further with exposure to the full clinical trial lifecycle and opportunities to develop your career.
- Be visible at scale in a global organisation where your contribution is recognised.
- Grow in a growing place , with expanding operations creating new opportunities across the business.
- Join a culture of curiosity where learning, collaboration and new ideas are encouraged every day.
- Access to benefits include Fitness Passport, Reward Hub discounts, wellbeing initiatives, recognition programs and EAP support.

About the Role

We are seeking to recruit a specialist medical practitioner to the role of Principal Investigator (PI) at Nucleus Network. This is a significant medical role and is focused on lead investigator responsibilities for early-phase clinical trials, including first-in-human studies.

This position reports to our Medical Director and will include involvement in the design, conduct and reporting of Phase 1 studies. PIs work as part of a larger team of medical officers, project managers, study coordinators, nurses and pharmacists at Nucleus Network that delivers safe clinical trials and high-quality trial data.

No prior Phase 1 trials experience is required,



and the appointee will be extensively trained and mentored in the PI role.

Key responsibilities

- Review clinical trial protocols and investigator brochures in depth
- Ensure the safe and effective implementation and performance of early-phase trials at our Brisbane unit, in association with the Brisbane Medical Director and Nucleus Network Chief Medical Officer
- Monitor safety during studies including the review and management of adverse events
- Provide medical services to participants of clinical trials
- Offer support to biotech and pharma companies on protocol design and study conduct
- Attend Safety Monitoring Committee meetings and contribute to dose-escalation decisions
- Provide medical advice to all departments of Nucleus Network
- Apply ICH Good Clinical Practice and applicable regulatory guidance to the practice of clinical trials
- Supervise and mentor junior medical officers at Nucleus Network
- Provide expertise and leadership if a medical emergency was to occur

Requirements

- Full Australian work rights
- Full AHPRA registration as a medical practitioner
- Good communication skills and ability to work effectively in a team
- An interest in the science and medicine of recent drug development
- FRACP or other fellowship of a relevant specialist college
- A PhD or other higher research degree may be an advantage, but is not essential for this role

All offers of employment are conditional upon:

- Right to work verification.
- Vaccination compliance, including Hepatitis B, Varicella, MMR and Pertussis, with serological testing for all participant-facing and sample-facing roles.

Nucleus Network is an equal opportunity employer. We value diverse backgrounds, inclusive teams and people who are driven by purpose, curiosity and care.

To learn more, visit Nucleus Network or follow us on LinkedIn Careers Page, Instagram and Facebook.

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📌 Principal Investigator (Clinical trials) (St Leonards)
🏢 Nucleus Network
📍 St Leonards