Principal Investigator | Clinical Trials
Join Nucleus Network as a Principal Investigator and help advance medicine while building a rewarding career in clinical research.
As the world's leading Phase 1 clinical trials specialist, with facilities across Australia, the USA, and the UK, we partner with global pharmaceutical and biotechnology companies to help bring current medicines to patients.
Why Join Nucleus Network?
Work with purpose
and contribute to research that improves lives worldwide.
Ask better questions and find smarter ways of working
in an environment that values innovation and continuous improvement.
Start here, go further
with exposure to the full clinical trial lifecycle and opportunities to develop your career.
Be visible at scale
in a global organization where your contribution is recognised.
Grow in a growing place
, with expanding operations creating new opportunities across the business.
Join a culture of curiosity
where learning, collaboration and new ideas are encouraged every day.
Access to benefits include Fitness Passport, Reward Hub discounts, wellbeing initiatives, recognition programs and EAP support.
About the Role
We are seeking to recruit a specialist medical practitioner to the role of
Principal Investigator
(PI) at Nucleus Network. This is a significant medical role and is focused on lead investigator responsibilities for early-phase clinical trials, including first-in-human studies.
This position reports to our Medical Director and will include involvement in the design, conduct and reporting of Phase 1 studies. PIs work as part of a larger team of medical officers, project managers, study coordinators, nurses and pharmacists at Nucleus Network that delivers safe clinical trials and high-quality trial data.
No prior Phase 1 trials experience is required,



and the appointee will be extensively trained and mentored in the PI role.
Key responsibilities
Review clinical trial protocols and investigator brochures in depth
Ensure the safe and effective implementation and performance of early-phase trials at our Brisbane unit, in association with the Brisbane Medical Director and Nucleus Network Chief Medical Officer
Monitor safety during studies including the review and management of adverse events
Provide medical services to participants of clinical trials
Offer support to biotech and pharma companies on protocol design and study conduct
Attend Safety Monitoring Committee meetings and contribute to dose‐escalation decisions
Provide medical advice to all departments of Nucleus Network
Apply ICH Good Clinical Practice and applicable regulatory guidance to the practice of clinical trials
Supervise and mentor junior medical officers at Nucleus Network
Provide expertise and leadership if a medical emergency was to occur
Requirements
Full Australian work rights
Full AHPRA registration as a medical practitioner
Good communication skills and ability to work effectively in a team
An interest in the science and medicine of new drug development
FRACP or other fellowship of a relevant specialist college
A PhD or other higher research degree may be an advantage, but is not essential for this role
All offers of employment are conditional upon:
Right to work verification.
Vaccination compliance, including Hepatitis B, Varicella, MMR and Pertussis, with serological testing for all participant‐facing and sample‐facing roles.
Nucleus Network is an equal opportunity employer. We value diverse backgrounds, inclusive teams and people who are driven by purpose, curiosity and care.
To learn more, visit Nucleus Network or follow us on LinkedIn Careers Page, Instagram and Facebook.
#J-*****-Ljbffr

📌 Principal Investigator | Clinical Trials (Brisbane)
🏢 Nucleus Network
📍 Brisbane