22 Sep
|
Nurix
|
Queensland
Job Description
Research Associate I, Pharmaceutical Development **~ Contract**
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Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development, and
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commercialization of small molecule therapies designed to modulate cellular protein levels as a novel
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treatment approach for cancer and immune disorders. Leveraging Nurix's extensive expertise in E3
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ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated
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discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of
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enzymes that can modulate proteins within the cell. Nurix's drug discovery approach is to either harness
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or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively
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decrease or increase cellular protein levels.
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Description
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Nurix is looking for a Research Associate I, Pharmaceutical Development to provide scientific, technical,
and hands-on support of drug discovery and product development related to small molecules from early discovery to clinical trial enabling studies.
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Prepare and characterize preclinical formulations in support of multiple programs.
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Perform stability and solubility testing using HPLC/UPLC.
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Assist with pre-formulation and formulation development for oral solid dosage forms.
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Contribute to internal and external presentations and publications.
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Qualifications
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Thorough understanding of basic chemistry principles
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Excellent basic quantitative laboratory skills including weighing, pipetting, and use of volumetric glassware
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Solid basic HPLC/UPLC skills and understanding (XRD and Mass Spec experience a plus)
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Excellent organizational and documentation skills
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Proficiency in Microsoft 365
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Experience in safe handling of potent compounds
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BS/BA or higher in chemistry, pharmaceutics, engineering, or related field with 2 - 4 years of industry experience
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Salary Range: 40/hr - 55/hr
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Location: Brisbane, CA - Onsite
📌 Research Associate I, Pharmaceutical Development ~ Contract (Queensland)
🏢 Nurix
📍 Queensland