We’re hiring a Principal Scientist in Cell Culture Development to join our team in Melbourne and play a key role in advancing biologics development.

This is a senior technical role where you’ll lead upstream process development, provide scientific direction, and help bring high-quality recombinant products from early development through to manufacturing readiness. You’ll work across platforms, collaborate cross-functionally, and contribute to impactful programs that support patient outcomes.

Your Responsibilities
Provide scientific leadership and technical expertise in cell culture process development, optimisation, and scale-up
Design and execute upstream development strategies across high-throughput and mid-scale platforms
Lead and contribute to experimental planning, execution, and data interpretation with robust scientific rigour
Support process development across the full lifecycle from clone selection through to process characterisation
Guide and mentor team members, sharing expertise and building capability
Contribute to regulatory documentation and submissions
Collaborate with cross-functional teams to enable tech transfer and manufacturing readiness

Skills & Experience




Postgraduate degree (MSc, PhD, MEng or equivalent) in a relevant field
Significant experience in cell culture process development (industry or advanced academic setting)
Proven track record working with recombinant protein production or similar systems
Comfortable working in cross-functional and multicultural teams

Experience With The Following Is Highly Regarded
Mammalian cell culture, particularly CHO systems
Early- and late-stage process development
Media development and metabolic modelling
Process optimisation aligned to product quality attributes
Bioreactor scale-up and scale-down
Technology transfer or implementation of manufacturing processes

Why join us?
Work on cutting-edge biologics development
Influence key scientific and technical decisions
Collaborate with a highly skilled, multidisciplinary team
Be part of work that ultimately supports patient impact

If you’re a scientist who enjoys combining deep technical expertise with leadership and collaboration, we’d love to hear from you.

Applications Close on September 30, 2026

📌 Principal Scientist, Cell Culture Development Melbourne
🏢 CSL
📍 Melbourne