Job Description
Operational Strategy Manager / Senior Manager - Clinical Research
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Location: Australia - Multiple locations available
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Employment: Permanent
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The Opportunity
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Our client is an established international clinical research organisation supporting biotechnology and pharmaceutical companies with the development and execution of clinical programmes globally.
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The organisation is seeking an experienced Operational Strategy Manager / Senior Manager to support the development of clinical trial strategies for new business opportunities, with a particular focus on Oncology.
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Unlike a traditional clinical project management position, this role sits predominantly at the pre-award and proposal stage. You will assess study requirements, feasibility intelligence and operational considerations to determine how a clinical programme can realistically and competitively be delivered.
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You will work closely with commercial and clinical stakeholders to develop the operational solution presented to prospective sponsors and will participate directly in sponsor discussions and proposal presentations.
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The Role
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You will provide operational leadership during the development of recent clinical research opportunities.
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Taking a Protocol Or Sponsor Requirement As The Starting Point, You Will Evaluate The Operational Implications Of The Study And Develop a Practical Execution Strategy Covering Areas Such As
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Country and site strategy
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Patient recruitment
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Study start-up
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Feasibility
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Timelines and resources
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Operational risks
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Budget assumptions
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Overall study delivery approach
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You will then translate these considerations into a clear proposal strategy and help communicate and defend the recommended approach with prospective sponsors.
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Key Responsibilities
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Develop operational strategies for prospective clinical studies based on protocol requirements, sponsor objectives and available feasibility intelligence.
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Evaluate potential countries, sites and recruitment approaches to determine appropriate study delivery models.
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Analyse feasibility information,



enrolment projections, start-up timelines and resource requirements.
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Translate clinical and operational data into practical recommendations for study execution.
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Develop the operational components of clinical trial proposals and supporting presentation materials.
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Participate in sponsor discussions, proposal presentations and bid defence activities.
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Explain and defend proposed operational approaches while responding to sponsor questions and challenges.
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Identify execution risks, dependencies and potential constraints during the proposal stage and recommend appropriate mitigation strategies.
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Balance operational feasibility against timelines, cost and commercial competitiveness.
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Review study budgets, resource assumptions and operational inputs to ensure they support the proposed execution strategy.
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Work with financial and commercial stakeholders to resolve inconsistencies between study requirements, operational assumptions and proposed budgets.
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Partner with feasibility, clinical operations, medical, finance, commercial and regional teams to build integrated solutions.
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Maintain alignment between study assumptions, timelines, risks, budgets and proposed delivery plans.
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Support the transition of successful proposals into delivery by ensuring key assumptions, commitments and risks are clearly transferred to operational teams.
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Use benchmarking, feasibility, market and historical operational information to strengthen recommendations.
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Contribute to the improvement of operational strategy frameworks, proposal processes and planning methodologies.
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Capture lessons from previous proposals and study opportunities to improve the quality and competitiveness of future solutions.
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What We Are Looking For
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This role requires someone who understands how clinical trials are actually delivered, but who can apply that knowledge strategically before a study has been awarded.
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The successful candidate should be comfortable analysing incomplete or complex information, developing a recommended operational approach and presenting the rationale behind that recommendation to both internal stakeholders and prospective sponsors.
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Key Requirements Include
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Bachelor's degree in Life Sciences, Clinical Research, Healthcare, Business or another relevant discipline.
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Minimum 7 years' relevant experience across clinical research operations, feasibility, operational strategy, proposal development or related areas.
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Strong understanding of clinical trial operations and study delivery.
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Good knowledge of study feasibility, site selection, country strategy, study start-up and patient recruitment considerations.
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Broad Oncology clinical research experience across multiple indications.
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Experience developing clinical study strategies, execution plans and/or operational components of proposals.
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Ability to interpret complex clinical and operational information and convert it into actionable recommendations.
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Strong cross-functional stakeholder management and influencing skills.
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Strong written communication, presentation and sponsor-facing capability.
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Ability to manage multiple proposals and priorities simultaneously.
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Experience providing technical guidance, coaching or mentoring to colleagues.
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Ability to travel domestically and internationally when required.
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Highly Desirable
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Previous experience supporting global clinical trial proposals.
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Participation in sponsor presentations and/or bid defence meetings.
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Experience reviewing clinical study budgets, resource models and operational assumptions.
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Exposure to commercial strategy, pricing or financial modelling within a CRO or clinical research environment.
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Experience working within international, matrixed clinical research teams.
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📌 (Snr) Operational Strategy Manager, Australia (New South Wales)
🏢 NexusHire Solutions
📍 New South Wales