Vice President / Senior Vice President, Global Development Leader (Bexobrutideg)
Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix's dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine's next chapter with a current script to outmatch disease.
We are seeking a brilliant, organized and highly motivated leader who will provide strategic and tactical medical leadership and will deliver key clinical and scientific leadership to clinical development programs while ensuring the highest standard for safety and compliance with regulatory requirements and standard procedures. The ideal candidate should have experience working in a fast-paced dynamic environment.The successful candidate will report to the Chief Medical Officer.The responsibilities of this leader are listed below.
Lead one or more Program teams comprised of functional representatives fromClinical Development(Clinical Operations, Medical Monitoring, Clinical Science),Research andTranslational Medicine, Regulatory, Technical Operations, Quality, and Commercial fromphase 1throughphase 3 and throughapproval and launch;serveas the single point of accountability for the BTK ProgramGlobal Development Team (GDT),



and to create and drive key program decisions through appropriate governance forums, where appropriate
As a member of theClinicalExecutiveManagement Team, partner with stakeholders to set transparent direction and executeagainst goals for a portfolio of clinical stage therapies, ensuring the development and execution of program strategy is in line with corporate strategy and goals
Drive the development and communication of program plans and development plan in partnership with the asset teams and program management
Facilitate cross-functional communication; drive strategic and operational alignment with the Program team, functional leads, and Executive Management Team
Identifychallenges and risks and prepare the team with mitigations to navigate through technical and program challenges as they arise
Develop orparticipatein the refinement/update of the Clinical Development Plan (CDP);act asor overseethe clinical leadsfor protocols and supportive activities to meet the CDP objectives
Provide medical oversight for ongoing clinical trials including regular review of clinical data to improve understanding of the molecule profile, including but not limited to safety and activity
Provide clinical oversight for Company operational staff and contract research organizations (CROs) in all areas related to the execution of therapeutic programs




Provideand or overseetraining and ongoing input to all members of the clinical team on medical and scientific issues related to theappropriate therapeuticfield
Provide medical support for all relevant regulatory discussions and activities, such as IND's and NDA/MAAs
Interact with principal investigators and opinion leaders tofacilitateclinical trials research
Refine and orestablishprocesses andmethods for design and implementation of applicable clinical protocols, data collectionsystemsand final reports
Data presentation to executive leaders, internal and external medical colleagues in one on one or large group settings (50+).
Required Qualifications
MD, board certified preferably inhematology/oncology
Requires at least 10 years' clinical trial experience in the setting ofpharmaceuticalindustry withdemonstratedexperience and involvement in clinical trial design or execution.In particular,Ph3clinical trial planning and execution.
Relevant clinical research experience in academic settings will be reviewedin light ofclinical development experience
Excellent communicator with proven leadership skills and the ability to interact in a cross functional environment
Comfortable in a fast-paced small company environment with minimal direction and able to adjust workload based upon changing priorities
Proven leadership experience leading high performing teams and individuals
Hands on leadershipapproachwill be best suited for this critical role
Experience working in a highly productive and high achieving collaboration
Fit with Nurix Culture and Values
Strong teamorientation; highly collaborative
Solutions and results-oriented focus
Hands-on approach; resourceful and open to diverse points of view
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📌 Vp/Svp, Global Development Leader (Brisbane)
🏢 Nurix
📍 Brisbane