About Us The team at Doherty Clinical Trials are driven to expand the horizons of early phase clinical trials, human challenge trials and medical research through the delivery of high-quality and safe clinical trials. We foster collaboration with stakeholders and value the essential role of clinical trial volunteers in enabling groundbreaking, innovative medical research that will translate to vaccines and therapies, especially for infectious diseases.

The Opportunity

Doherty Clinical Trials is seeking experienced Registered Nurses to join our casual nursing team, with a particular focus on night shift coverage.

This is a casual opportunity, working night shifts on a rotating roster. Ideally, you will be available to work an average of 2 to 3 night shifts per week, with shifts offered based on DCT’s operational requirements and your availability.

This role is suited to an experienced nurse who is confident working overnight and demonstrates strong clinical judgement, initiative and adaptability. You will play an important role in ensuring the safety and wellbeing of clinical trial participants while supporting the delivery of high-quality clinical research.

This is a unique opportunity to contribute to groundbreaking medical research while providing compassionate, participant-centred care in a highly specialised clinical trial environment.

The Role The Registered Nurse is responsible for delivering safe, evidence-based and person-centred care within a multidisciplinary clinical setting during overnight shifts.

Responsibilities include providing clinical care, monitoring and assessing clinical trial participants, responding appropriately to changes in participant condition, coordinating care activities and maintaining a safe and effective clinical environment.

You will also ensure accurate and timely electronic documentation and work closely with the broader clinical and research teams to support the delivery of clinical trial protocols.

About You To be successful in this position,



you will be an experienced and confident Registered Nurse with strong clinical assessment and decision-making skills.

You will be comfortable working night shifts and able to work both independently and collaboratively within a multidisciplinary environment.

You will provide comprehensive, high-quality clinical care, including assessment, planning, implementation and evaluation, while responding promptly and appropriately to changes in participant condition.

A commitment to professional conduct, participant safety and adaptability is essential.

You Will Possess

- Availability and flexibility to work night shifts on a rotating roster, ideally averaging 2 to 3 shifts per week.
- Strong clinical assessment, critical thinking and decision-making skills.
- Confidence working independently during overnight shifts while collaborating effectively with the broader clinical team.
- Strong clinical documentation skills and attention to detail.
- Intermediate computer literacy, including the ability to use electronic health record systems.
- Excellent verbal and written communication skills.
- A adaptable and adaptable approach within a clinical research environment.

Qualifications and Experience

- Current registration as a Registered Nurse (Division 1) with AHPRA.
- Minimum of 2 years post-registration experience in an acute, community or subacute healthcare setting.
- Previous experience in a clinical trial setting is highly desirable.
- Proficiency in Microsoft Office.
- Strong IT, application and systems skills. DCT is a highly digitised clinical trial unit, and confidence working across electronic systems is required.
- ALS competency (desirable)

Requirements To safeguard the health and safety of participants, staff and other healthcare workers, vaccination against certain diseases is strongly recommended for all employees. Must hold, or be willing to obtain, all required clearances (e.g. National Police Check).

Shortlisting will commence immediately, so please submit your application without delay.

Applications close 5pm Friday 18 September 2026.

📌 Casual Night Duty Nurse (Melbourne)
🏢 The Engaged Space
📍 Melbourne