Postdoctoral Scientist – Regulatory SystemsOnsite, Darlinghurst, Sydney, NSWReporting to: Faculty, Regulatory Systems – Wong LabAbout youYou are an ambitious computational biologist who is excited by big biological questions and motivated by the opportunity to uncover how our genes are regulated across development, ageing and disease.
You enjoy working at the intersection of genomics, statistics and machine learning, and thrive on transforming complex datasets into meaningful biological discoveries.You'll bring strong analytical and programming skills, a collaborative mindset and a curiosity-driven approach to research.
Whether you've already established yourself in the single-cell genomics space or are looking to take the next step in your research career, you are keen to contribute to impactful science within a supportive and highly cooperative environment.The roleThe Regulatory Systems Laboratory, led by Associate Professor Emily Wong, and help answer fundamental questions about how gene regulation is encoded within DNA.
Working with cutting-edge single-cell and multiomic datasets, you'll investigate how gene-regulatory mechanisms change across different cell types, during ageing and in response to genetic variation.This is an exciting opportunity to work alongside experimental and computational researchers, applying advanced statistical and machine learning approaches to large-scale genomic data.
You'll have the opportunity to drive innovative research projects, contribute to high-impact publications and collaborate with leading national and international research partners.What we will trust you withLeading the computational analysis of large-scale single-cell and multiomic genomic datasetsIntegrating diverse genomics datasets to uncover changes in cell states and gene regulationApplying and developing computational, statistical and machine learning approaches to answer complex biological questionsBuilding robust,



reproducible analysis pipelines and maintaining high standards of data management and documentationTranslating computational findings into biological insights in partnership with experimental researchersContributing to scientific publications, conference presentations and grant applicationsCollaborating with researchers across the Institute and external partner organisationsMentoring students and junior researchers and contributing to a positive, inclusive laboratory cultureDoes this sound like you?
Completed, or are close to completing, a PhD in computational biology, bioinformatics, genomics, statistics, computer science or a related quantitative disciplineExperience analysing single-cell genomic datasets such as scRNA-seq, scATAC-seq or multiome dataConfident using Python and/or R and working with large datasets in Linux or high-performance computing environmentsStrong knowledge of genomics, genetics and the biological mechanisms that regulate gene expressionAbility to critically evaluate data, solve complex problems and work independently to drive projects forwardA publication record appropriate to your career stage, including first-author publications or preprintsYou communicate effectively and enjoy collaborating with researchers from diverse scientific backgroundsExperience with machine learning, deep learning, regulatory genomics or ageing biology will be highly regardedAbout usThe Victor Chang Cardiac Research Institute (the Institute)



is dedicated to finding cures for cardiovascular disease and is one of the most respected heart research facilities in the world.
Renowned for the quality of its breakthroughs, the Institute was established in **** and has grown to a team of more than 200 researchers from around the globe, working across five divisions.A global centre-of-excellence, it integrates Cardiac Physiology and Transplantation, Developmental and Stem Cell Biology, Molecular Cardiology and Biophysics, Structural and Computational Biology, as well as Vascular Biology.
At the Institute, we translate our discoveries into new diagnostics, prevention, and treatment of cardiovascular disease - reducing the incidence, severity, and impact of heart disease.What you will be proud ofBeing part of an Institute that is not only dedicated to finding cures for cardiovascular disease, but one that also strives to ensure our employees and students enjoy a outstanding working environment.
We value and are committed to providing a safe working environment that embraces diversity, gender equity and promote flexible working arrangements for all employees.We encourage Aboriginal and Torres Strait Islander people to apply.
We also welcome applicants with diverse educational backgrounds, qualified knowledge, personality types, thinking styles and life experiences.
If you have a disability or special need that requires accommodation, please let us know.What we offerSalary packaging (including a $15,900 tax-free component, plus meal and entertainment allowances, holiday accommodation/venue hire plus many more).
Banking & lifestyle benefits with Commonwealth Bank, including lending offers, discounts from participating retailers and financial wellbeing webinars.Fitness PassportExcellent environment with new state-of-the-art equipment.Collaborative team environmentContinuous learning and development opportunities
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📌 Postdoctoral Scientist – Regulatory Systems (New South Wales)
🏢 Victor Chang Cardiac Research Institute
📍 New South Wales