PhD Scholarship: Synthetic gene circuits for controllable production of antibody and gene therapy medicines (Queensland)

PhD Scholarship: Synthetic gene circuits for controllable production of antibody and gene therapy medicines (Queensland)

09 Aug
|
University Of Queensland
|
Queensland

09 Aug

University Of Queensland

Queensland

Biological sciences » Biological engineering

Technology » Biotechnology

Organisation/Company University of Queensland Department School of Chemical Engineering Research Field Biological sciences » Biological engineering Technology » Biotechnology Chemistry » Biochemistry Researcher Profile First Stage Researcher (R1) Positions PhD Positions Application Deadline 12 Aug 2026 - 00:00 (Australia/Brisbane) Country Australia Type of Contract Temporary Job Status Full time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Biologic medicines, such as antibody drugs and gene therapies, are grown inside living mammalian cells. Yield and consistency are limited by how little control we have over those cells once production begins.

This project builds genetic switches inside the cell that turn production on and off during a run. The work has three parts:

- Design: build the genetic parts that act as switches. This includes logic gates that respond to two inputs at once, so production happens only under the conditions you choose.
- Cell engineering: put those switches into mammalian cells and use them to control the manufacture of products made from more than one protein chain.
- Bioprocessing: tune the culture conditions and the switching strategy for the best yield and product quality.

Nobody arrives knowing all three. You will be trained in whatever is new to you. If the project interests you but you are unsure whether your background fits, email the principal supervisor before you apply.

Research environment

You will be based in the Biomedical Engineering Laboratory in the Andrew N. Liveris Building at UQ's St Lucia campus.

The laboratory has the mammalian cell culture suites, molecular biology facilities, microscopy and flow cytometry the project needs, and you will use them daily.

The project is co-supervised by Professor Lars Nielsen at the Australian Institute for Bioengineering and Nanotechnology, so you will work in two research groups rather than one.

You will also be connected to the National Biologics Facility, Australia's national centre for biopharmaceutical development.

A cell line you engineer at the bench can be tested there at industrial scale.

- living stipend of $39,220 per annum tax free (2026 rate), indexed annually





Your application will be assessed on a competitive basis.

We take into account your:

- previous academic record
- publication record
- honours and awards
- employment history.

A working knowledge of mammalian cell culture and characterisation and/or molecular biology (DNA cloning, RNA and protein methods) would be of benefit to someone working on this project.

You will demonstrate academic achievement in the field(s) of biomedical sciences, molecular biology, biochemical and/or chemical engineering, or a closely related discipline.and the potential for scholastic success.

A background or knowledge of synthetic biology, bioprocessing, or analytical techniques (e.g., mass spectrometry, ELISA) is highly desirable.

Research Field Biological sciences » Biological engineering Education Level Master Degree or equivalent

Research Field Technology » Biotechnology Education Level Master Degree or equivalent

Research Field Chemistry » Biochemistry Education Level Master Degree or equivalent

Skills/Qualifications

Your application will be assessed on a competitive basis.

We take into account your:

- previous academic record
- publication record
- honours and awards
- employment history.

A working knowledge of mammalian cell culture and characterisation and/or molecular biology (DNA cloning, RNA and protein methods) would be of benefit to someone working on this project.

You will demonstrate academic achievement in the field(s) of biomedical sciences, molecular biology, biochemical and/or chemical engineering, or a closely related discipline.and the potential for scholastic success.

A background or knowledge of synthetic biology, bioprocessing, or analytical techniques (e.g., mass spectrometry, ELISA) is highly desirable.

Specific Requirements

Specific requirements — international applicants

Academic background. You need a qualifying degree in a relevant discipline completed no more than ten years ago: a Master of Philosophy, a bachelor's degree with at least honours class IIA,



or a coursework master's with a GPA of 5.65 on UQ's 7-point scale together with demonstrated research experience. Qualifications from outside Australia are assessed on their equivalence, and the standing of your institution within its own system is taken into account, not only its global ranking.

English language proficiency. These are laboratory-based projects with no clinical component, so the standard UQ requirement applies: IELTS 6.5 overall with at least 6.0 in every sub-band, or an accepted equivalent. Results from separate test sittings cannot be combined.

You may not need a test at all. If your most recent degree was taught and assessed in English and you completed it within five years of your intended commencement, you may be able to meet the requirement by deeming instead. Applicants from some countries are required to hold a current test result regardless, because of Australian visa criteria. Ask before you pay for a test.

Visa and commencement. UQ has no remote or distance HDR programme. You must study on a UQ campus in Brisbane, and you cannot commence from overseas. Student visa processing takes four to six months on average and longer for some countries, so your commencement will be set to a research quarter that allows for it - in practice, six months or more after an offer is issued. You must arrive and commence within the first fourteen days of your research quarter; time lost beforehand is not added to the end of your candidature.

Health cover. Single Overseas Student Health Cover is included in the scholarship. Cover for a partner or dependants is not, and you would need to fund that yourself as a condition of your visa.

Sanctions. Applicants who are citizens of, or resident in, a country on Australia's autonomous sanctions list require an additional compliance assessment before an offer can be made. This is a standard check, not a barrier in itself, but it adds time.

What you do not need at expression of interest stage. A complete document set, a finalised research proposal, or a test result if deeming may apply. Submit the EOI, and any gaps can be addressed before the full application. If you are unsure whether you meet these requirements, write and ask: [email protected]

Languages ENGLISH Level Excellent

Research Field Biological sciences » Biological engineering Years of Research Experience 1 - 4

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📌 PhD Scholarship: Synthetic gene circuits for controllable production of antibody and gene therapy medicines (Queensland)
🏢 University Of Queensland
📍 Queensland

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