AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery,developmentand commercialisation of prescription medicines for some of the world’s most serious diseases. Butwe’remore than one of the world’s leading pharmaceutical companies. At AstraZeneca, we are pioneering new frontiers byidentifyingand treating patients earlier, working towards the aim ofeliminatingcancer as a cause of death.

Come and join our AZ team where you will play a pivotal role in this exciting period of development!!

Pharmaceutical

Sciences is a function within the AstraZeneca Biopharmaceuticals R&D; unit that builds innovative, effective solutions by transforming molecules into investigative medicines meeting unmet needs of future patients.

Early Chemical

Development (ECD) is CMC department with responsibility for early phase Drug Substance. The department’s responsibilities span from early engagement with Discovery Chemistry groups to manufacture of Phase II Clinical material, and its key skill areas include Analytical Chemistry, Crystallisation, Isotope Chemistry, Large-Scale Laboratory (Kilo-Lab) Manufacturing, Process Chemistry, Process Design,



Process Engineering, Route Design and Separation Science. We’relooking for a highly experienced Process Chemist to join the team working on our peptide-containing clinical programs.

These programs include pure-play therapeutic peptide projects, as well as projects involving peptide conjugates (such as antibody-peptide conjugates and oligonucleotide-peptide conjugates). The role will sit within ECD’s New Modalities team, with a focus on delivering against our TIDES-based early clinical-phase project portfolio, working closely with our CMC Project Leaders and in collaboration between our late-phase development teams and our internal Discovery TIDES colleagues. The individual will have extensive process chemistry development,manufacturingand project leadership experience, and this must include considerableexpertisein developing peptide chemistry for CMC applications.

A passion for working in new / emerging scientific areas and developing solutions to technical and project challenges is a key requirement for the role.

📌 Associate Principal Scientist –PeptideDevelopmentChemistry - Pharmaceutical Sciences (PS) (Perth)
🏢 ONE NUCLEUS
📍 Perth