Could you be our next Senior Director, Immunology and Translation? This hybrid position is located in our Waltham, MA or Melbourne, Australia offices, requiring onsite presence three days a week. You will report to the Research Therapeutic Area Lead, Immunology/Transplant and Vaccines.

Responsibilities

Scientific Leadership & Disease Area Expertise

- Serve as the primary scientific expert and internal champion for one or more immunology disease areas, including rheumatology, neuroimmunology, and rare dermatology.
- Translate deep mechanistic understanding of immune pathology into actionable therapeutic hypotheses and target identification strategies.
- Maintain a comprehensive view of the competitive landscape, emerging science, and unmet medical need across assigned disease areas.
- Represent CSL Behring at key scientific conferences, advisory boards, and KOL meetings; build and leverage a broad external network of thought leaders, clinical investigators, and academic collaborators.
- Drive end‑to‑end asset progression from ideation through first‑in‑disease designation, integrating scientific rationale, translational endpoints, patient population selection, and regulatory strategy.
- Lead or co‑lead target and asset evaluation activities including preclinical data package reviews, mechanism‑of‑action assessments, and translational feasibility analyses.
- Provide scientific input to IND‑enabling studies, proof‑of‑concept study designs, and Phase 1/1b protocol development.
- Collaborate with the discovery and translational teams to define disease‑relevant biomarkers, pharmacodynamic readouts, and patient stratification strategies for early clinical programs.




- Actively contribute to R&D; programs as a subject‑matter expert and provide guidance for the clinical development pathway.
- Collaborate with the Research Therapeutic Area Lead, RPLs, and Immunology core team members to develop and maintain a best‑in‑class immunology portfolio.

Cross‑Functional Collaboration & Strategic Input

- Partner with Business Development to assess in‑licensing, partnering, and acquisition opportunities within the immunology space, providing scientific due diligence leadership.
- Contribute to Target Product Profiles (TPPs), integrated development plans, and portfolio reviews.
- Provide disease area expertise to regulatory submissions, clinical study reports, and scientific communications.
- Work collaboratively with Medical Affairs, Clinical Operations, and translational colleagues to align development strategies.

Qualifications

- MD, DO, or PhD in Immunology or a closely related discipline.
- 12+ years of experience in drug development within a biotech, pharmaceutical, or academic environment.
- Demonstrated experience in preclinical to first‑in‑disease (or equivalent early clinical milestone) in immunology.
- Deep scientific expertise in the immunological mechanisms underpinning autoimmune and inflammatory diseases.
- Established and active network in drug development with recognized relationships across rheumatology, neuroimmunology, and/or dermatology communities.
- Proven track record in evaluating preclinical and clinical assets, including target assessment, data package review, and go/no‑go decision‑making.
- Solid ability to synthesize complex scientific data and communicate strategy clearly to diverse audiences, including senior leadership.

The expected base salary range for this position is $302,000 – $350,000, with additional incentive compensation and equity available.

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📌 Senior Director, Immunology and Translation (Melbourne)
🏢 CSL
📍 Melbourne